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Latest Advances in Our Lab:

Tumor-derived exosomes antagonize innate antiviral immunity.

Nature Immunology 2018 

Breast cancer metastasis suppressor OTUD1 deubiquitylates SMAD7. 

Nature Communications 2017

YAP antagonizes innate antiviral immunity and is targeted for lysosomal degradation through kinase-IKKe mediated phosphorylation. 

Nature Immunology. 2017  

FAF1 phosphorylation by AKT accumulates TGF-β type II receptor and drives breast cancer metastasis. 

Nat Communications. 2017