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2013年回浙大后的工作:

1)    Shengduo Liu#, Shasha Chen#, Xinran Li, Shiying Wu, Qian Zhang, Qiuheng Jin, Lin Hu, Ruyuan Zhou, Zhengyang Yu, Fansen Meng, Siwen Wang, Yaowei Huang, Sheng Ye, Li Shen, Zongping Xia, Jian Zou, Xin-Hua Feng, Pinglong Xu*. Lck/Hck/Fgr-mediated tyrosine phosphorylation negatively regulates TBK1 to restrain innate antiviral responses. Cell Host & Microbe, 2017, 21(6): 754-768. (IF: 14.946) (Link @ Cell Host & Microbe)

Free PDF download: https://authors.elsevier.com/a/1VDAU6t8JEREeG

2)     Qian Zhang#, Fansen Meng#, Shasha Chen, Steven W. Plouffe, Shiying Wu, Shengduo Liu, Xinran Li, Ruyuan Zhou, Junxian Wang, Bin Zhao, Jianming Liu, Jun Qin, Jian Zou, Xin-Hua Feng, Kun-Liang Guan, and Pinglong Xu*. Hippo signaling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade. Nature Cell Biology, 2017, 19(4): 362-374. DOI: 10.1038/ncb3496. (IF: 20.06) (Link @ Nature Cell Biology)

Previewed in Nature Cell Biology: Hippo interferes with antiviral defences, Nature Cell Biology, 2017, 19(4): 267-269.

Highlighted by Science Signaling as Editor’s Choice: Hippo-sized antiviral defenses, Science Signaling, 2017, 10(474): eaan4043.

 

3)     Pinglong Xu, Xia Lin, and Xin-Hua Feng*. Posttranslational regulation of Smads. Cold Spring Harbor Perspectives in Biology, 2016, 8(12): a022087. (Invited Review) (IF: 9.173) (Link @ CSH Perspect Biol) (PDF)

 

4)     Weiwen Xiang#, Qian Zhang#, Xia Lin, Shiying Wu, Yao Zhou, Fansen Meng, Yunyun Fan, Mu Xiao, Zongping Xia, Jian Zou, Xin-Hua Feng*, and Pinglong Xu*. PPM1A silences cytosolic RNA sensing and antiviral defense through direct dephosphorylation of MAVS and TBK1. Science Advances, 2016, 2(7): e1501889. (Link @ Science Advances) (PDF)

 

5)     Fansen Meng, Ruyuan Zhou, Shiying Wu, Qian Zhang, Qiuheng Jin, Yao Zhou, Steven W. Plouffe, Shengduo Liu, Hai Song, Zongping Xia, Bin Zhao, Sheng Ye, Xin-Hua Feng, Kun-Liang Guan, Jian Zou, and Pinglong Xu*. Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation. Genes & Development, 2016, 30(9): 1087-1100. (IF: 10.042) (Link @ Genes & Development) (PDF)

 

6)      Shuchen Gu, Yanjing Liu, Bowen Zhu, Ke Ding, Tso-Pang Yao, Fenfang Chen, Lixing Zhan, Pinglong Xu, Marcelo Ehrlich, Tingbo Liang, Xia Lin, Xin-Hua Feng*. Loss of alpha-tubulin acetylation is associated with TGF-beta-induced epithelial-mesenchymal transition. Journal of Biological Chemistry, 2016, 291(10): 5396-405. (IF: 4.258)

 

7)     Xin-Hua Feng*, Pinglong Xu, and Xia Lin. TGF-β Signaling, Methods in Molecular Biology. 2015, Springer Protocols, Humana Press. ISBN: 978-1-4939-2965-8. (Book) (Link @ Springer)

 

8)     Fenfang Chen, Xia Lin, Pinglong Xu, Zhengmao Zhang, Yanzhen Chen, Chao Wang, Jiahuai Han, Bin Zhao, Mu Xiao, Feng X-H*. Nuclear Export of Smads by RanBP3L Regulates BMP Signaling and Mesenchymal Stem Cell Differentiation. Molecular and Cellular Biology, 2015, 35(10): 1700-11. (IF: 4.777)

 

9)      Pinglong Xu*, Samantha Bailey-Bucktrout, Ying Xi, Daqi Xu, Dan Du, Qian Zhang, Weiwen Xiang, Jianming Liu, Andrew Melton, Dean Sheppard, Harold A. Chapman, Jeffery A. Bluestone, and Rik Derynck*. Innate antiviral host defense attenuates TGF-β function through IRF3-mediated suppression of Smad signaling. Molecular Cell, 2014, 56(6): 723-737. (IF: 14.018) (Link @ Mol Cell) (PDF)

Previewed by Dr. Richard Flavell: Resemble and Inhibit: When RLR Meets TGF-β, Molecular Cell, 2014, 56(6): 719-720.

Highlighted by Science Signaling as Editor’s Choice: Enhancing and inhibiting TGF-β signaling in infection, Science Signaling, 2015, 8(359): 6549.

 

回国前工作:

10)   Pinglong Xu, Jianming Liu, Masayo Yumoto and Rik Derynck. TACE activation by MAPK-mediated regulation of cell surface dimerization and TIMP3 association. Science Signaling, 2012, 5(222): ra34. (IF: 6.337)(PDF)

 

11)   Pinglong Xu, Jianming Liu, and Rik Derynck. Post-translational regulation of TGF-β receptor and Smad signaling. FEBS Letters, 2012, 586(14): 1872-84. (IF: 3.341) (PDF)

Invited review in special issue: Sorting the TGF-β labyrinth. 

 

12)  Pinglong Xu and Rik Derynck. Direct activation of TACE-mediated ectodomain shedding by p38 MAP kinase regulates EGF receptor-dependent cell proliferation. Molecular Cell, 2010, 37(4): 551-66. (IF: 14.194) (PDF)

Recommended by Faculty of 1000.

 

13)  Cheng Liu#, Pinglong Xu#, Samy Lamouille, Jian Xu, and Rik Derynck. TACE-mediated ectodomain shedding of the type I TGF-β receptor downregulates TGF-β signaling. Molecular Cell, 2009, 35(1): 26-36. (#, co-first authors) (IF: 14.608) (PDF)

Highlight by Science Signaling as Editor’s Choice: Another TGF-β Desensitization Strategy. Science Signaling, 2009, 2(80): p.ec247.

 

14)   Ping-Long Xu, Yun-Qin Liu, Shi-Fang Shan, Yu-Ying Kong, Qing Zhou, Mei Li, Jian-Ping Ding, You-Hua Xie, and Yuan Wang. Molecular mechanism for the potentiation of the transcriptional activity of human liver receptor homologue 1 by steroid receptor coactivator-1. Molecular Endocrinology, 2004, 18(8): 1887-905. (IF: 5.807)

 

15)  Xu Ping-Long, Kong Yu-Ying, Xie You-Hua, and Wang Yuan. Corepressor SMRT specifically represses the transcriptional activity of orphan nuclear receptor hB1F/LRH-1. Acta Biochimica et Biophsica Sinica, 2003, 35(10) : 897-903. (IF2015: 2.124)

 

16)  Xu Ping-Long, Shan Shi-Fang, Kong Yu-Ying, Xie You-Hua, and Wang Yuan. Characterization of a strong repression domain in the hinge region of orphan nuclear receptor hB1F/LRH-1. Acta Biochimica et Biophsica Sinica, 2003, 35(10): 909-916. (IF2015: 2.124)

 

17)  Cheng-Kang Zhang, Wei Lin, Yan-Ning Cai, Ping-Long Xu, Hui Dong, Mei Li, Yu-Ying Kong, Gang Fu, You-Hua Xie, Guyang Matthew Huang, and Yuan Wang. Characterization of the genomic structure and tissue-specific promoter of the human nuclear receptor NR5A2 (hB1F) gene. Gene, 2001, 273(2): 239-249. (IF2015: 2.319)

 

18)  Bao Jin-Ku, Wu Chuan-Fang, Lu Hui, Zhou Hong, Zeng Zhong-Kui, Xu Ping-Long, and Zou Jian. The effect of metal ion and denaturant on conformation and function of Polygonatum cyrtonema Hua. Lectin II. Journal of Sichuan University, 2000, 12(6): 112-117.

 

19)  Bao Jin-Ku, Xu Ping-Long, Zhou Hong, Zeng Zhong-Kui, and Zou Jian. The relation between chemical modification tyrosine and biological activity of Polygonatum cyrtonema Hua. Lectin II. Chinese Journal of Biochemistry and Molecular Biology, 2000, 16(1): 142-146.