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2013年回浙大后的工作:

1)    Lin Hu, Jiafeng Xu, Xiaomei Xie, Yiwen Zhou, Panfeng Tao, Haidong Li, Xu Han, Chong Wang, Jian Liu, Pinglong Xu, Dante Neculai, and Zongping Xia. Oligomerization-Primed Coiled-coil Domain Interaction with Ubc13 Confers Processivity to TRAF6 Ubiquitin Ligase Activity. Nature Communications, 2017, 8:814. (IF: 12.124) 2017_NC.pdf


2)    Yi Yu, Shuchen Gu, Wenjian Li, Chuang Sun, Fenfang Chen, Mu Xiao, Lei Wang, Dewei Xu, Ye Li, Chen Ding, Zongping Xia, Yi Li, Sheng Ye, Pinglong Xu, Bin Zhao, Jun Qin, Ye-Guang Chen, Xia Lin, and Xin-Hua Feng. Smad7 enables STAT3 activation and promotes pluripotency independent of TGF-β signaling. Proc Natl Acad Sci U S A, 2017, 114(38): 10113-10118. (IF: 9.661)  2017_PNAS.pdf


3)    Shengduo Liu#, Shasha Chen#, Xinran Li, Shiying Wu, Qian Zhang, Qiuheng Jin, Lin Hu, Ruyuan Zhou, Zhengyang Yu, Fansen Meng, Siwen Wang, Yaowei Huang, Sheng Ye, Li Shen, Zongping Xia, Jian Zou, Xin-Hua Feng, Pinglong Xu*. Lck/Hck/Fgr-mediated tyrosine phosphorylation negatively regulates TBK1 to restrain innate antiviral responses. Cell Host & Microbe, 2017, 21(6): 754-768. (IF: 14.946) (Link @ Cell Host & Microbe) 2017_CHOM.pdf


4)     Qian Zhang#, Fansen Meng#, Shasha Chen, Steven W. Plouffe, Shiying Wu, Shengduo Liu, Xinran Li, Ruyuan Zhou, Junxian Wang, Bin Zhao, Jianming Liu, Jun Qin, Jian Zou, Xin-Hua Feng, Kun-Liang Guan, and Pinglong Xu*. Hippo signaling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade. Nature Cell Biology, 2017, 19(4): 362-374. DOI: 10.1038/ncb3496. (IF: 20.06) (Link @ Nature Cell Biology) 2017_NCB.pdf

Previewed in Nature Cell Biology: Hippo interferes with antiviral defences, Nature Cell Biology, 2017, 19(4): 267-269.

Highlighted by Science Signaling as Editor’s Choice: Hippo-sized antiviral defenses, Science Signaling, 2017, 10(474): eaan4043.

 

5)     Pinglong Xu, Xia Lin, and Xin-Hua Feng*. Posttranslational regulation of Smads. Cold Spring Harbor Perspectives in Biology, 2016, 8(12): a022087. (Invited Review) (IF: 9.173) (Link @ CSH Perspect Biol) (PDF)

 

6)     Weiwen Xiang#, Qian Zhang#, Xia Lin, Shiying Wu, Yao Zhou, Fansen Meng, Yunyun Fan, Mu Xiao, Zongping Xia, Jian Zou, Xin-Hua Feng*, and Pinglong Xu*. PPM1A silences cytosolic RNA sensing and antiviral defense through direct dephosphorylation of MAVS and TBK1. Science Advances, 2016, 2(7): e1501889. (Link @ Science Advances) (PDF)

 

7)     Fansen Meng, Ruyuan Zhou, Shiying Wu, Qian Zhang, Qiuheng Jin, Yao Zhou, Steven W. Plouffe, Shengduo Liu, Hai Song, Zongping Xia, Bin Zhao, Sheng Ye, Xin-Hua Feng, Kun-Liang Guan, Jian Zou, and Pinglong Xu*. Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation. Genes & Development, 2016, 30(9): 1087-1100. (IF: 10.042) (Link @ Genes & Development) (PDF)

 

8)      Shuchen Gu, Yanjing Liu, Bowen Zhu, Ke Ding, Tso-Pang Yao, Fenfang Chen, Lixing Zhan, Pinglong Xu, Marcelo Ehrlich, Tingbo Liang, Xia Lin, Xin-Hua Feng*. Loss of alpha-tubulin acetylation is associated with TGF-beta-induced epithelial-mesenchymal transition. Journal of Biological Chemistry, 2016, 291(10): 5396-405. (IF: 4.258)

 

9)     Xin-Hua Feng*, Pinglong Xu, and Xia Lin. TGF-β Signaling, Methods in Molecular Biology. 2015, Springer Protocols, Humana Press. ISBN: 978-1-4939-2965-8. (Book) (Link @ Springer)

 

10)     Fenfang Chen, Xia Lin, Pinglong Xu, Zhengmao Zhang, Yanzhen Chen, Chao Wang, Jiahuai Han, Bin Zhao, Mu Xiao, Feng X-H*. Nuclear Export of Smads by RanBP3L Regulates BMP Signaling and Mesenchymal Stem Cell Differentiation. Molecular and Cellular Biology, 2015, 35(10): 1700-11. (IF: 4.777)

 

11)      Pinglong Xu*, Samantha Bailey-Bucktrout, Ying Xi, Daqi Xu, Dan Du, Qian Zhang, Weiwen Xiang, Jianming Liu, Andrew Melton, Dean Sheppard, Harold A. Chapman, Jeffery A. Bluestone, and Rik Derynck*. Innate antiviral host defense attenuates TGF-β function through IRF3-mediated suppression of Smad signaling. Molecular Cell, 2014, 56(6): 723-737. (IF: 14.018) (Link @ Mol Cell) (PDF)

Previewed by Dr. Richard Flavell: Resemble and Inhibit: When RLR Meets TGF-β, Molecular Cell, 2014, 56(6): 719-720.

Highlighted by Science Signaling as Editor’s Choice: Enhancing and inhibiting TGF-β signaling in infection, Science Signaling, 2015, 8(359): 6549.

 

回国前工作:

10)   Pinglong Xu, Jianming Liu, Masayo Yumoto and Rik Derynck. TACE activation by MAPK-mediated regulation of cell surface dimerization and TIMP3 association. Science Signaling, 2012, 5(222): ra34. (IF: 6.337)(PDF)

 

11)   Pinglong Xu, Jianming Liu, and Rik Derynck. Post-translational regulation of TGF-β receptor and Smad signaling. FEBS Letters, 2012, 586(14): 1872-84. (IF: 3.341) (PDF)

Invited review in special issue: Sorting the TGF-β labyrinth. 

 

12)  Pinglong Xu and Rik Derynck. Direct activation of TACE-mediated ectodomain shedding by p38 MAP kinase regulates EGF receptor-dependent cell proliferation. Molecular Cell, 2010, 37(4): 551-66. (IF: 14.194) (PDF)

Recommended by Faculty of 1000.

 

13)  Cheng Liu#, Pinglong Xu#, Samy Lamouille, Jian Xu, and Rik Derynck. TACE-mediated ectodomain shedding of the type I TGF-β receptor downregulates TGF-β signaling. Molecular Cell, 2009, 35(1): 26-36. (#, co-first authors) (IF: 14.608) (PDF)

Highlight by Science Signaling as Editor’s Choice: Another TGF-β Desensitization Strategy. Science Signaling, 2009, 2(80): p.ec247.

 

14)   Ping-Long Xu, Yun-Qin Liu, Shi-Fang Shan, Yu-Ying Kong, Qing Zhou, Mei Li, Jian-Ping Ding, You-Hua Xie, and Yuan Wang. Molecular mechanism for the potentiation of the transcriptional activity of human liver receptor homologue 1 by steroid receptor coactivator-1. Molecular Endocrinology, 2004, 18(8): 1887-905. (IF: 5.807)

 

15)  Xu Ping-Long, Kong Yu-Ying, Xie You-Hua, and Wang Yuan. Corepressor SMRT specifically represses the transcriptional activity of orphan nuclear receptor hB1F/LRH-1. Acta Biochimica et Biophsica Sinica, 2003, 35(10) : 897-903. (IF2015: 2.124)

 

16)  Xu Ping-Long, Shan Shi-Fang, Kong Yu-Ying, Xie You-Hua, and Wang Yuan. Characterization of a strong repression domain in the hinge region of orphan nuclear receptor hB1F/LRH-1. Acta Biochimica et Biophsica Sinica, 2003, 35(10): 909-916. (IF2015: 2.124)

 

17)  Cheng-Kang Zhang, Wei Lin, Yan-Ning Cai, Ping-Long Xu, Hui Dong, Mei Li, Yu-Ying Kong, Gang Fu, You-Hua Xie, Guyang Matthew Huang, and Yuan Wang. Characterization of the genomic structure and tissue-specific promoter of the human nuclear receptor NR5A2 (hB1F) gene. Gene, 2001, 273(2): 239-249. (IF2015: 2.319)

 

18)  Bao Jin-Ku, Wu Chuan-Fang, Lu Hui, Zhou Hong, Zeng Zhong-Kui, Xu Ping-Long, and Zou Jian. The effect of metal ion and denaturant on conformation and function of Polygonatum cyrtonema Hua. Lectin II. Journal of Sichuan University, 2000, 12(6): 112-117.

 

19)  Bao Jin-Ku, Xu Ping-Long, Zhou Hong, Zeng Zhong-Kui, and Zou Jian. The relation between chemical modification tyrosine and biological activity of Polygonatum cyrtonema Hua. Lectin II. Chinese Journal of Biochemistry and Molecular Biology, 2000, 16(1): 142-146.