The 107th West Lake Symposium--Forum on Protein Modification by Ubiquitin and Ubiquitin-like Molecules in Health and Disease

编辑: Date:2014/05/04

The 107th West Lake Symposium on Protein Modification by Ubiquitin and Ubiquitin-like Molecules in Health and Disease will be held in Hangzhou on May 14, 2014. This symposium will bring together international leaders in the field, who will present their most recent work and discuss its implications in human disease and therapeutic development.

        The following topics will be covered:

1.   Sumoylation in signaling, gene transcription, development and human diseases;
2.   Ubiquitination in DNA repair, immune response, tumorogenesis;
3.   Hijacking of ubiquitin signaling by pathogens;
4.   Cancer metabolism and therapeutics.
Date and time: 09:00-17:20, May 14, 2014
Location: Multi-function Hall 395, Nano Building, Zijingang Campus, Zhejiang University  

Presentation program:
09:00 – 12:20
ModulatorXin-Hua Feng
09:00 – 09:15
Welcome Remarks
09:15 – 10:00
Tony Hunter
Keynote Speaker
Salk Institute for Biological Studies, La Jolla, CA
SUMO-mediated Regulation of Transcription
10:00 – 10:30
Edward T.H.Yeh
The University of Texas MD Anderson Cancer Center, Houston, TX
SUMO: Implications for Human Diseases
10:30 – 10:50
Group Photo & Coffee Break
10:50 – 11:20
Hsing-Jien Kung
National Health Research Institutes, Taipei
Metabolism and Cancer Therapeutics: Targeting Arginine Addiction of Cancer Cells
11:20 – 11:50
Michael Matunis
Johns Hopkins University, Baltimore, MD
The Role of SUMO Proteases in Controlling Progression through Mitosis
11:50 – 12:20
Hsiu-Ming Shih
Institute of Biomedical Sciences, Academia Sinica, Taipei
Acetylation Controls Selective Substrates for SUMO Binding and Conjugation
12:20 – 13:30
13:30 – 15:40
ModulatorZongping Xia
13:30 – 14:00
Jinrong Peng
Zhejiang University, Hangzhou
Def and Calpain3 Defines a Nucleolar Protein Degradation Pathway which is Essential for Cell Cycle Progression
14:00 – 14:30
Ye-Guang Chen
Tsinghua University, Beijing
Fine Control of TGF-b Receptor Stability by Ubiquitination and Neddylation
14:30 – 15:00
Shao-Cong Sun
The University of Texas MD Anderson Cancer Center, Houston, TX
Ubiquitin Signaling in the Regulation of Immune Responses
15:00 – 15:20
Yong Cang
Zhejiang University, Hangzhou
CRL4ACRBN E3 Ubiquitin Ligase Restricts BK Channel Activity and Prevents Epileptogenesis
15:20 – 15:40
Jun Huang
Zhejiang University, Hangzhou
SIVA1 Directs the E3 Ubiquitin Ligase RAD18 for PCNA Mono-ubiquitination
15:40 – 15:50
Coffee Break
15:50 – 17:20
ModulatorYong Cang
15:50 – 16:20
Yi Sun
Zhejiang University, Hangzhou
SAG/RBX2 E3 Ubiquitin Ligase in Angiogenesis and Tumorigenesis: Therapeutic Applications
16:20 – 16:40
Anyong Xie
Zhejiang University, Hangzhou
Roles of the TRIP12 Ubiquitin Ligase in DNA Replication Stress Response
16:40 – 17:00
Zongping Xia
Zhejiang University, Hangzhou
Activation of IKK by HTLV-1 TAX
17:00 – 17:20
Yongqun Zhu
Zhejiang University, Hangzhou
Structural Insights into Bacterial Regulation of the Host Ubiquitin Pathway
Organizer: Life Sciences Institute, Zhejiang University   
Dr. Zongping Xia:Tel: 0571-88981625E-mail:
Ms. Yun Zheng:Tel: 0571-88981336, E-mail:
Ms. Ying Liu:Tel: 0571-88981373, E-mail: