The 107th West Lake Symposium on Protein Modification by Ubiquitin and Ubiquitin-like Molecules in Health and Disease will be held in Hangzhou on May 14, 2014. This symposium will bring together international leaders in the field, who will present their most recent work and discuss its implications in human disease and therapeutic development.
The following topics will be covered:
1. Sumoylation in signaling, gene transcription, development and human diseases;
2. Ubiquitination in DNA repair, immune response, tumorogenesis;
3. Hijacking of ubiquitin signaling by pathogens;
4. Cancer metabolism and therapeutics.
Date and time: 09:00-17:20, May 14, 2014
Location: Multi-function Hall 395, Nano Building, Zijingang Campus, Zhejiang University
Presentation program:
| 09:00 – 12:20 | Modulator：Xin-Hua Feng |
| 09:00 – 09:15 | Welcome Remarks |
| 09:15 – 10:00 | Tony Hunter Keynote Speaker Salk Institute for Biological Studies, La Jolla, CA SUMO-mediated Regulation of Transcription |
| 10:00 – 10:30 | Edward T.H.Yeh The University of Texas MD Anderson Cancer Center, Houston, TX SUMO: Implications for Human Diseases |
| 10:30 – 10:50 | Group Photo & Coffee Break |
| 10:50 – 11:20 | Hsing-Jien Kung National Health Research Institutes, Taipei Metabolism and Cancer Therapeutics: Targeting Arginine Addiction of Cancer Cells |
| 11:20 – 11:50 | Michael Matunis Johns Hopkins University, Baltimore, MD The Role of SUMO Proteases in Controlling Progression through Mitosis |
| 11:50 – 12:20 | Hsiu-Ming Shih Institute of Biomedical Sciences, Academia Sinica, Taipei Acetylation Controls Selective Substrates for SUMO Binding and Conjugation |
| 12:20 – 13:30 | Lunch |
| 13:30 – 15:40 | Modulator：Zongping Xia |
| 13:30 – 14:00 | Jinrong Peng Zhejiang University, Hangzhou Def and Calpain3 Defines a Nucleolar Protein Degradation Pathway which is Essential for Cell Cycle Progression |
| 14:00 – 14:30 | Ye-Guang Chen Tsinghua University, Beijing Fine Control of TGF-b Receptor Stability by Ubiquitination and Neddylation |
| 14:30 – 15:00 | Shao-Cong Sun The University of Texas MD Anderson Cancer Center, Houston, TX Ubiquitin Signaling in the Regulation of Immune Responses |
| 15:00 – 15:20 | Yong Cang Zhejiang University, Hangzhou CRL4ACRBN E3 Ubiquitin Ligase Restricts BK Channel Activity and Prevents Epileptogenesis |
| 15:20 – 15:40 | Jun Huang Zhejiang University, Hangzhou SIVA1 Directs the E3 Ubiquitin Ligase RAD18 for PCNA Mono-ubiquitination |
| 15:40 – 15:50 | Coffee Break |
| 15:50 – 17:20 | Modulator：Yong Cang |
| 15:50 – 16:20 | Yi Sun Zhejiang University, Hangzhou SAG/RBX2 E3 Ubiquitin Ligase in Angiogenesis and Tumorigenesis: Therapeutic Applications |
| 16:20 – 16:40 | Anyong Xie Zhejiang University, Hangzhou Roles of the TRIP12 Ubiquitin Ligase in DNA Replication Stress Response |
| 16:40 – 17:00 | Zongping Xia Zhejiang University, Hangzhou Activation of IKK by HTLV-1 TAX |
| 17:00 – 17:20 | Yongqun Zhu Zhejiang University, Hangzhou Structural Insights into Bacterial Regulation of the Host Ubiquitin Pathway |
Organizer: Life Sciences Institute, Zhejiang University
Contact:
Dr. Zongping Xia：Tel: 0571-88981625, E-mail: xia2010@zju.edu.cn
Ms. Yun Zheng：Tel: 0571-88981336, E-mail: yunzh@zju.edu.cn
Ms. Ying Liu：Tel: 0571-88981373, E-mail: lyzju@zju.edu.cn
