Meeting Web:
https://s.eqxiu.cn/s/7tPvclfJ?bt=yxy&eip=true
http://lsi.zju.edu.cn/2023/1117/c25130a2827839/page.htm
http://lsi.zju.edu.cn/lsien/2023/1118/c25023a2828203/page.htm
Meeting Coordinators:
Ms. Li Huang (黄莉), +86-571-8820-6358 (tel), 15968906914 (mobile)
Ms. Yun Zheng (郑云), +86-571-8820-8052 (tel), 13588238187 (mobile)
Dr. Bo Yuan (袁博), 15700080260 (mobile)
Dr. Yi Yu (余奕), 18958123013 (mobile)
MEETING VENUE & ACCOMMODATION
Hilton Hangzhou Qiandao Lake Resort (杭州千岛湖滨江希尔顿酒店： 浙江省杭州市淳安县千岛湖环湖北路600号)
| 1st day, Tuesday, December 19, 2023 | ||||
9:00 – 12:00 | Registration Networking/Free Discussion | |||
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13:50 - 14:00 | Opening Remark (Chair: Xin-Hua Feng) | |||
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Session 1 | Signaling and Cancer Therapy (Chair: Ye-Guang Chen) | |||
14:00 - 14:40 | Rik Derynck, University of California – San Francisco | |||
| TGF-b in cancer progression and immunotherapy | |||
14:40 - 15:20 | Carl-Henrik Heldin, Uppsalla University | |||
| Targeting the pro-tumorigenic effects of TGF-b in tumor treatment | |||
15:20 - 15:50 | Long Zhang | |||
| Targeting secreation of EV-TβRII prevents T cell exhaustion and enhances tumor immunotherapy | |||
15:50 - 16:00 | Coffee/tea break | |||
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Session 2 | Signaling Crosstalks (Chair: Xin-Hua Feng) | |||
16:00 - 16:30 | Ye-Guang Chen | |||
Regulation of intentional epithelium homeostasis by BMP | ||||
16:30 - 17:00 | Kunxin Luo | |||
| Regulation of Hippo/TAZ signaling by phase separation | |||
17:00 - 17:30 | Qiaoran Xi | |||
| The intricate dance of TGF-β signaling and epigenetic regulation: implications for diffuse intrinsic pontine glioma | |||
17:30 - 18:00 | Jianping Jin | |||
| The roles of ubiquitin ligases in TGF-β signaling and beyond | |||
18:00 - 18:20 | Xiaohua Yan | |||
| The Smad2/3-TEAD4 dialogue in regulating gene transcription and liver cancer progression | |||
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2nd day, Wednesday, December 20, 2023 | ||||
Session 3 | Signaling and Immunity (Chair: Chen Dong and WanJun Chen) | |||
8:30 - 9:00 | Chen Dong | |||
TGF-b regulation of T cell fate decisions | ||||
9:00 - 9:30 | WanJun Chen, | |||
| TGF-b regulation of T cells in autoimmunity and cancer | |||
9: 30 - 10:00 | Bing Su | |||
| Cross-talk between the MAPK and TGF-b signals in immune and vascular function | |||
10:00 - 10:30 | Li Yang | |||
| Myeloid TGF-b signaling in cancer and stroke | |||
10:30- 10:40 | Coffee & Tea Break | |||
10:40 - 11:10 | Ying Zhang | |||
| TGF-b-regulated alternative splicing during EMT and cancer progression | |||
11:10 - 11:40 | Pinglong Xu | |||
| Recent advances in organ fibrosis | |||
11:40 - 12:00 | Yi Yu | |||
| Noncanonical functions of Smad7 | |||
12:00 - 14:00 | Lunch & Break | |||
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Session 4 | Signaling, Development and Diseases | |||
14:00 - 17:30 | Discussion: TGF-b physiology and translational potential | |||
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3nd day, Thursday, December 21, 2023 | ||||
Session 5 | Signaling, Development and Diseases (Chair: Li Yang) | |||
9:00 – 9:30 | Seong-Jin Kim | |||
Mast4 serves as a mediator of TGF-b and Wnt signal transduction in regulating chondro-osteogenic differentiation of mesenchymal stromal cells | ||||
9:30 - 10:00 | Duanqing Pei | |||
Cell fate decision by BMP4-SALL4-NuRD axis | ||||
10:00 - 10:30 | Li Yu | |||
| The role of TGF-b in migrasome biogenesis | |||
10:30 - 10:50 | Mu Xiao | |||
| Smad4 sequestered in SFPQ condensates prevents TGF-β tumor-suppressive signaling | |||
10:50 - 11:10 | Shuchen Gu | |||
| FAM134C is an autophagy receptor for BMP type I receptor degradation through the autophagy-lysosome pathway | |||
11:10 - 11:30 | Pengfei Xu | |||
| Sculpting the Vertebrate Embryo: Insights from TGF-β Signaling | |||
11:30 - 12:00 | Xin-Hua Feng | |||
| Role of Smad8 in cardiomyocyte differentiation | |||
12:00 – | Lunch & departure | |||
