The Lin Lab is interested in developing new chemical reactions, novel molecular probes and tools to precisely manipulate proteins in living cells at molecular level, and applying these innovative chemical biology tools in basic biology researches and clinic applications. We are particularly interested in probing proteins modifications and proteins life cycle with chemical and biological methods. The specific directions are summarized below:

●  Studying proteins post-translational modifications, as well as their writers, erasers and binders 

●  New strategies for studying proteins life cycle, and their regulation pathways 

●  Protein modification methods on rare natural amino acids, and their post-translation modifications