Welcome                                            

The lab started in 2014 Jan at the life sciences institute, Zhejiang University. Our studies focus on the mechanisms of cellular signaling pathway in tumor progression and immunity; We are particularly interested in post-translational-modifications (PTMs) in proteins. 

Latest Advances in Our Lab: 

AARS1/2 senses L-lactate to regulate cGAS as global lysine lactyltransferase
Nature. 2024 

TRIM28: a SUMO-E3 for SARS2-NP
Nature Communications. 2024

iProphos: a novel platform for proteomic data analysis
Molecular & Cellular Proteomics. 2024

Mechanism of Wapl interaction with Cohesin complex
Proceedings of the National Academy of Science (PNAS). 2024

Consensus statement on EV liquid biopsy
Clinical Chemistry and Laboratory Medicine. 2024

Review on ketogenic diet and cancer
Science China Life Sciences. 2024

Review on mucosal immune response in biology and disease 
Signal Transduction and Targeted Therapy. 2024

Highlight on PARP1-DNA con-condensation
Signal Transduction and Targeted Therapy. 2024 

Highlight on a high-resolution spatiotemporal mapping
Signal Transduction and Targeted Therapy. 2024

Highlight on serotonin signaling
MedComm. 2024

Highlight on Kacme that marks chromatin
MedComm-Future Medicine. 2024