2012年论文

科学研究

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1.Distinct gating mechanisms revealed by the structures of a multi-ligand gated K⁺ channel
2.Structural Basis of the PNRC2-Mediated Link between mRNA Surveillance and Decapping
3.The Ighmbp2 helicase structure reveals the molecular basis for disease-causing mutations in DMSA1
4.Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses
5.Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling
6.Exome sequencing identifies NMNAT1 mutations as a cause of Leber congenital amaurosis
7.Structural Basis of Heparan Sulfate-Specific Degradation by Heparinase III
8.Crystal structures of Lsm3, Lsm4 and Lsm5/6/7 from Schizosaccharomyces pombe
9.Protein Phosphatase 4 Cooperates with Smads to Promote BMP Signaling in Dorsoventral Patterning of Zebrafish Embryos
10.The Hippo pathway regulates stem cell proliferation, self-renewal, and differentiation
11.Genetic Abolishment of Hepatocyte Proliferation Activates Hepatic Stem Cells
12.RAD18-BRCTx interaction is required for efficient repair of UV-induced DNA damage
13.cell detachment activates the hippo pathway via cytoskeleton reorganization to induce anoikis