肖睦

	肖　睦　博士浙江大学生命科学研究院副教授电话：86-571-88981540 Email： Mu_Xiao@zju.edu.cn
教育背景
1997-2001 武汉大学生命科学学院生物学基地班　　学士 2001-2006 武汉大学病毒国家实验室生物化学　　博士 2006-2011 美国罗切斯特大学(University of Rochester, NY) 博士后
工作经历
2011-今浙江大学生命科学研究院副教授博士生导师
研究方向
研究非编码RNA以及其结合蛋白在干细胞分化和癌细胞发生中的作用机制。
代表性论文
1. Guowei Wu, Mu Xiao, Chunxin Yang, Yi-Tao Yu, 2011, U2 snRNA is inducibly pseudouridylated at novel sites by Pus7p and snR81 RNP, Embo J ;30(1):79-89 ( Co-First auther) 2. Mu Xiao,Chunxing Yang, Peter Schattner, Yi-Tao Yu, 2008, Functionality and substrate specificity of human box H/ACA guide RNAs.RNA 15(1): 176–186. 3. Mu Xiao, Tingting Li, Xiaoyan Yuan, Yuan Shang, and Yi Zhang, 2005, A peripheral element assembles the compact core structure essential for group I self-splicing. Nucleic Acids Research33: 4602-4611. 4. Mu Xiao, Michael J. Leibowitz and Yi Zhang. 2003, Concerted folding of a Candida ribozyme to the catalytically active structure posterior to a rapid RNA compaction. Nucleic Acids Research 31: 3901-3908. (Cover topic) 5. Libin Zhang, Mu Xiao, Chen Lu and Yi Zhang. 2005, Fast formation of the P3-P7 pseudoknot: a strategy for efficient folding of the catalytically active ribozyme. RNA 11(1): 59-69. 6. Yanfei Jiang, Mu Xiao, Ping Yin and Yi Zhang 2006, Monovalent cations use multiple mechanisms to resolve ribozyme misfolding.RNA 12(4):561-566 7. Jiehua Zhou, Jiangyu Wu, Xiaoxuan Liu, Fanqi Qu, Mu Xiao, Yi Zhang, Laurence Charles, Cheng-cai Zhang and Ling Peng 2006, Cooperative binding and self-assembling behavior of cationic low molecular-weight dendrons with RNA molecules. Org Biomol Chem. 4, 581-5. 8. Shunji Jia, Fangyan Dai, Di Wu, Xia Lin, Cencan Xing, Yu Xue, Ying Wang, Mu Xiao, Wei Wu, Xin-Hua Feng, Anming Meng, 2012, Protein Phosphatase 4 Cooperates with Smads to Promote BMP Signaling in Dorsoventral Patterning of Zebrafish Embryos. Dev. Cel.22(5): 1065-1078

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肖睦