已发表的研究论文：

1.  Ting Wang^*, Xiaonan Song^*, Jiaxing Tan^*, Wei Xian, Xingtong Zhou, Mingru Yu, Xiaofei Wang, Yan Xu, Ting Wu, Keke Yuan, Yu Ran, Bing Yang, Gaofeng Fan, Xaoyun Liu^#, Yan Zhou^#, Yongqun Zhu^#. Legionella effector LnaB is a phosphoryl-AMPylase that impairs phosphosignalling. Nature. 2024 May 22. doi: 10.1038/s41586-024-07573-z.

2.  Jiaxing Tan^*, Xing Zhang^*,#, Xiaofei Wang^*, Caihuang Xu^*, Shenghai Chang, Hangjun Wu, Ting Wang, Huihui Liang, Haichun Gao, Yan Zhou, Yongqun Zhu^#. Structural Basis of Assembly and Torque Transmission of the Bacterial Flagellar Motor. Cell. 2021 May 13;184(10):2665-2679.

3.  Yan Zhou^*, Chunfeng Huang^*, Li Yin, Muyang Wan, Xiaofei Wang, Lin Li, Yanhua Liu, Zhao Wang, Panhan Fu, Ni Zhang, She Chen, Xiaoyun Liu, Feng Shao, Yongqun Zhu^#. N^ε-Fatty acylation of Rho GTPases by a MARTX toxin effector. Science. 2017 Oct 27;358(6362):528-531.

4．Muyang Wan^*, Xiaofei Wang^*, Chunfeng Huang, Dandan Xu, Zhao Wang，Yan Zhou, Yongqun Zhu^#. A bacterial effector deubiquitinase specifically hydrolyses linear ubiquitin chains to inhibit host inflammatory signalling. Nature Microbiology. 2019 Aug;4(8):1282-1293.

5. Fujie Yan^*, Chunfeng Huang^*, Xiaofei Wang Jiaxing Tan, Sen Cheng, Muyang Wan, Zhao Wang, Shuangyu Wang, Shuhui Luo, Arong Li, Xing Guo, Mingguang Feng, Xiaoyun Liu, Yongqun Zhu^#, Yan Zhou^#. Threonine ADP-ribosylation of ubiquitin by a bacterial effector family blocks host ubiquitination. Molecular Cell. 2020 May 21;78(4):641-652.

6.  Xiaofei Wang^*, Deqiang Yao^*, Jin-Gen Xu, A-Rong Li, Jianpo Xu, Panhan Fu, Yan Zhou, Yongqun Zhu^#. Structural basis of Cas3 inhibition by the bacteriophage protein AcrF3. Nature Structural & Molecular Biology. 2016 Sep;23(9):868-70.

7.  Jianpo Xu^*, Dandan Xu^*, Muyang Wan, Li Yin, Xiaofei Wang, Lijie Wu, Yanhua Liu, Xiaoyun Liu, Yan Zhou, Yongqun Zhu^#. Structural insights into the roles of the IcmS-IcmW complex in the type IVb secretion sytem of Legionella pneumophila. Proc Natl Acad Sci USA. 2017 Dec 19; 114(51): 13543-48.

8. Xiaofei Wang^*, Xiangyu Chen^*, Jiaxing Tan, Shuai Yue, Runhong Zhou, Yan Xu, Yao Lin, Yang Yang, Yan Zhou, Kai Deng^#, Zhiwei Chen^#, Lilin Ye^#, Yongqun Zhu^#. 35B5 antibody potently neutralizes SARS-CoV-2 Omicron by disrupting the N-glycan switch via a conserved spike epitope. Cell Host Microbe. 2022 Mar 29:S1931-3128(22)00165-2.

9.  Na Dong^*, Yongqun Zhu^*,#, Qiuhe Lu, Liyan Hu, Yuqing Zheng, Feng Shao#. Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell. 2012 Aug 31;150(5):1029-41. (co-first author & co-corresponding author)

10.  Zhaofeng Yan^*, Meng Yin^*, Dandan Xu, Yongqun Zhu^#, Xueming Li^#. Structural insights into the secretin translocation channel in the type II secretion system. Nature Structural & Molecular Biology. 2017 Feb;24(2):177-183. (# corresponding authors)

11.  Panhan Fu^*, Xiaoqing Zhang^*, Mengmeng Jin^*, Li Xu, Chong Wang, Zongping Xia, Yongqun Zhu^#. Complex Structure of OspI and Ubc13: The Molecular Basis of Ubc13 Deamidation and Convergence of Bacterial and Host E2 Recognition. PLOS Pathogens. 2013 Apr;9(4):e1003322.

12.  Jin-Gen Xu^*, Chunfeng Huang^*, Zhengfeng Yang, Mengmeng Jin, Panhan Fu, NiZhang, Jian Luo, Dali Li, Mingyao Liu, Yan Zhou^#, Yongqun Zhu^#. Crystal Structure of LGR4-Rspo1 Complex: Insights into the divergent mechanisms of ligand recognition by Leucine-rich G-protein-coupled receptors (LGRs). Journal of Biological Chemistry. 2015 Jan 23;290(4):2455-65.

13. Jiaxing Tan, Shuhui Luo, Yan Zhou, Yongqun Zhu^#. Modulation of Host Ubiquitination Pathways by Pathogenic Bacterial Effector Proteins. Progress in Biochemistry and Biophysics.  2020,47(02).

14.  Muyang Wan, Yan Zhou, Yongqun Zhu^#. Subversion of Macrophage Functions by Bacterial Protein Toxins and Effectors. Curr Issues Mol Biol. 2017 Sep 6;25:61- 80.

15.  Yan Zhou, Yongqun Zhu^#. Diversity of bacterial manipulation of the host ubiquitin pathways. Cellular Microbiology. 2015 Jan;17(1):26-34.

16.  Deli Huang, Xinru Zheng, Zi-An Wang, Xin Chen, Wan-Ting He, Yingying Zhang, Jin-Gen Xu, Hang Zhao, Wenke Shi, Xin Wang, Yongqun Zhu, Jiahuai Han. MLKL channel in necroptosis is octamer formed by tetramers in a dyadic process. Mol Cell Biol. 2016 Dec 5.

17. Fujie Yan, Yongqun Zhu, Yan Zhu^#. Legionella pneumophila balances ubiquitin transglutamination. EMBO J. 2020 Feb 17;39(4):e104258.

18.  Kai Xu^*, Chan YP^*, Bradel-Tretheway B^*, Akyol-Ataman Z^*, Yongqun Zhu^*, Dutta S, Yan L, Feng Y, Wang LF, Skiniotis G, Lee B, Zhou ZH, Broder CC, Aguilar HC^#, Nikolov DB^#. Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly. PLOS Pathogens. 2015 Dec 8;11(12):e1005322.

19.  Qing Yu, Liyan Hu, Qing Yao, Yongqun Zhu, Na Dong, Da-Cheng Wang, Feng Shao^#. Structural analyses of Legionella LepB reveal a new GAP fold that catalytically mimics eukaryotic RasGAP. Cell Research. 2013 Jun;23(6):775-87

20. Yongqun Zhu^*, Liyan Hu, Yan Zhou, Qing Yao, and Feng Shao^#. Structural mechanism of host Rab1 activation by the bifunctional Legionella type IV effector SidM/DrrA. Proc Natl Acad Sci USA. 2010 Mar 9; 107(10):4699-704.

21.  Qing Yao^*, Jixin Cui^*, Yongqun Zhu, Guolun Wang, Liyan Hu, Chengzu Long, Ran Cao, Xinqi Liu, Niu Huang, She Chen, Liping Liu, and Feng Shao^#. A bacterial type III effector family uses the papain-like hydrolytic activity to arrest the host cell cycle. Proc Natl Acad Sci USA. 2009 Mar 10; 106(10):3716-21.

22.  Yongqun Zhu^*, Hongtao Li^*, Jiayi Wang, Liyan Hu, Yan Zhou, Liping Liu, Feng Shao^#. Structure of a Shigella effector reveals a new class of ubiquitin ligases. Nature Structural & Molecular Biology. 15(12):1302-8, Dec 2008.

23.  Yongqun Zhu^*, Hongtao Li^*, Chengzu Long, Liyan Hu, Hao Xu, Liping Liu, She Chen, Da-Cheng Wang^#, and Feng Shao^#. Structural Insights into the Enzymatic Mechanism of the Pathogenic MAPK Phosphothreonine Lyase. Molecular Cell. 28, 899–913, Dec 14, 2007.

24.  Yong-Qun Zhu^*, De-Yu Zhu^*, Lei Yin, Ying Zhang, Clemens Vonrhein, and Da-Cheng Wang^#. Crystal Structure of Human Spermidine/Spermine N1-Acetyltransferase (hSSAT): The First Structure of a New Sequence Family of Transferase Homologous Superfamily. PROTEINS. 63:1127–1131, 2006.

25.  De-Yu Zhu^*, Yong-Qun Zhu^*, Ren-Huai Huang, Ye Xiang, Na Yang, Hong-Xia Lu, Gen-Pei Li, Qi Jin, and Da-Cheng Wang^#. Crystal Structure of the Copper Homeostasis Protein (CutCm) from Shigella flexneri at 1.7 Å Resolution: The First Structure of a New Sequence Family of TIM Barrels. PROTEINS.58:764–768, 2005.

26.  De-Yu Zhu^*, Yong-Qun Zhu^*, Ye Xiang and Da-Cheng Wang^#. Optimizing Protein Crystal Growth through Dynamic Seeding. Acta Cryst. D. (2005)61, 772-775.

27.  Yong-Qun Zhu^*, De-Yu Zhu^*, Hong-Xia Lu, Na Yang, Gen-Pei Li, Da-Cheng Wang^#. Purification and Preliminary Crystallographic Studies of CutC, a Novel Copper Homeostasis Protein from Shigella flexneri. Protein & Peptide Letters. 12, 823-826, 2005.