2024
Xue J, Fang W, Zhang Y, Liu Y, Ran Y, Yang B, Xu P, Fang D, Ye C (2024) Oxidation-responsive demethylation of PP2A activates transcriptional programs for antioxidative defense. In prep
Peng X*, Xie Y*, Pan H, Shen W, Chen J, Jiang H#, Ye C# (2024) Dietary methionine deprivation enhances renal resilience against ischemia-reperfusion injury through modulation of glucose oxidation. Under review.
Yang S*, Wang Y*, Huang S, Jiang C, Ye C# (2024) Temporal oscillation of phospholipids promotes metabolic efficiency. Under review.
Qiu H*, Miao C*, Ye C# (2024) An adaptive organelle triad houses lipid droplets for dynamic regulation. Under review
Qiu H and Ye C# (2024) Phospholipid biosynthesis: An unforeseen modulator of nuclear metabolism. Under review.
Wu H, Cao R, Wen X, Fan J, Wang Y, Hu H, Ji S, Zhang Y, Ye C, Xie W, Zhang J, Xu H, Fu X (2024) Lysosomal catabolic activity promotes the exit of murine totipotent 2-cell state by silencing early-embryonic retrotransposons. Dev Cell. doi:10.1016/j.devcel.2024.10.018
Qi LF, Liu S, Fang Q, Qian C, Peng C, Liu Y, Yang P, Wu P, Shan L, Cui Q, Hua Q, Yang S, Ye C, Yang W, Li P, Xu X (2024) Ginsenoside Rg3 restores mitochondrial cardiolipin homeostasis via GRB2 to prevent Parkinson's disease. Adv Sci. e2403058.
Chen Q, Peng C, Xie R, Xu H, Su Z, Yilihan G, Wei X, Yang S, Shen Y, Ye C, Jiang C (2024) Placental and fetal enrichment of microplastics from disposable paper cups: Implications for metabolic and reproductive health druing pregnancy. J Hazard Mater. 478: 135527.
★Zhu Y*, Tong X*, Xue J*, Qiu H, Zheng D, Zheng DQ, Tu ZC, Ye C# (2024) Phospholipid biosynthesis modulates nucleotide metabolism and reductive capacity. Nat. Chem. Biol. doi:10.1038/s41589-024-01689-z.
★Xue J and Ye C# (2024) The role of lipoylation in mitochondrial adaptation to methionine restriction. BioEssays.46(6):e2300218.
Zhang L, Zhao J, Lam SM, Chen L, Gao Y, Wang W, Xu Y, Tan T, Yu H, Zhang M, Liao X, Wu M, Zhang T, Huang J, Li B, Zhou QD, Shen N, Lee HJ, Ye C, Li D, Shui G, Zhang J (2024) Low-input lipidomics reveals lipid metabolism remodeling during early mammalian embryo development. Nat Cell Biol. 26(2):278-293.
Wang A, Chen C, Mei C, Liu S, Xiang C, Fang W, Zhang F, Xu Y, Chen S, Zhang Q, Bai X, Lin A, Neculai D, Xia B, Ye C, Zou J, Liang T, Feng XH, Li X, Shen C, Xu P (2024) Innate immunity sensing of lysosomal dysfunction drives multiple lysosomal storage disorders. Nat Cell Biol. 26(2):219-234.
Hu G, Gu L, Wang R, Jian Q, Lv K, Xia M, Lai M, Shen T, Hu J, Yang S, Ye C, Zhang X, Wang Y, Xu X, Zhang F (2024) Ethanolamine as a biomarker and biomarker-based therapy for diabetic retinopathy in glucose-well-controlled diabetic patients. Sci Bull. 69(12):1920-1935.
Liu S, Han S, Wang C, Chen H, Xu Q, Feng S, Wang Y, Yao J, Zhou Q, Tang X, Lin L, Hu L, Davidson AJ, Yang B, Ye C, Yang F, Mao J, Tong C, Chen J, Jiang H (2024) MAPK1 mediates MAM disruption and mitochondrial dysfunction in diabetic kidney disease via the PACS-2-dependent mechanism. Int J Bio Sci. 20(2):569-584.
2023
★Fang W*, Jiang L*, Zhu Y*, Yang S, Qiu H, Cheng J, Liang Q, Tu ZC, Ye C# (2023) Methionine restriction constrains lipoylation and activates mitochondria for nitrogenic synthesis of amino acids. Nature Commun.14:2504.
★Zhang Y*, Zhou Y*, Fang W*, Zhu H, Cao W, Ye C#, Zhang D#, Lee HJ# (2023) Spatial sterol metabolism unveiled by stimulated Raman imaging. Front. Chem. 11:1166313.
2022
Zhou Q, Hao B, Cao X, Gao L, Yu Z, Zhao Y, Zhu M, Zhong G, Chi F, Dai X, Mao J, Zhu Y, Rong P, Chen L, Bai X, Ye C, Chen S, Liang T, Li L, Feng XH, Tan M, Zhao B (2022) Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha. Mol. Cell 82(24):4700-4711.
★Yang S, Xue J, Ye C# (2022) Protocol for rapid and accurate quantification of phospholipids using LC-MS. STAR Protocols 3(4):101769.
Li S*, Han S*, Zhang Q, Zhu Y, Zhang H, Wang J, Zhao Y, Zhao J, Su L, Li L, Zhou D, Ye C, Feng XH, Liang T, Zhao B (2022). FUNDC2 promotes liver tumorigenesis by inhibiting MFN1-mediated mitochondrial fusion. Nat. Commun. 13(1):3486.
Peng X, Wang X, Shao X, Wang Y, Feng S, Wang C, Ye C, Chen J, Jiang H (2022). Serum Metabolomics Benefits Discrimination Kidney Disease Development in Type 2 Diabetes Patients. Front Med. 9:819311.
★Fang W*, Zhu Y*, Yang S, Tong X, Ye C# (2022) Reciprocal regulation of phosphatidylcholine synthesis and H3K36 methylation programs metabolic adaptation. Cell Reports 39(2):11067.
Zhao JS#, Shi S, Qu HY, Keckesova Z, Cao ZJ, Yang LX, Yu X, Feng L, Shi Z, Krakowiak J, Mao RY, Shen YT, Fan YM, Fu TM, Ye C, Xu D, Gao X, You J, Li W, Liang T#, Lu Z#, Feng YX# (2022) Glutamine synthetase licenses APC/C-mediated mitotic progression to drive cell growth. 4(2):239-253.
2021
Huang LJ, Mao XT, Li YY, Liu DD, Fan KQ, Liu RB, Wu TT, Wang HL, Zhang Y, Yang B, Ye C, Zhong JY, Chai RJ, Cao Q, Jin J (2021) Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn's disease. 54(8):1728-1744.
Wang W, Ren S, Lu Y, Chen X, Qu J, Ma X, Deng Q, Hu Z, Jin Y, Zhou Z, Ge W, Zhu Y, Yang N, Li Q, Pu J, Chen G, Ye C, Wang H, Zhao X, Liu Z, Zhu S (2021). Inhibition of Syk promotes chemical reprogramming of fibroblasts via metabolic rewiring and H2S production. EMBO J. 40 (11) e106771.
2020
Li Y, Lou W, Grevel A, Böttinger L, Liang Z, Ji J, Patil VA, Liu J, Ye C, Hüttemann M, Becker T, Greenberg ML (2020) Cardiolipin-deficient cells have decreased levels of the iron-sulfur biogenesis protein frataxin. J. Biol. Chem. 295(33):11928-11937.
Haws SA, Yu D, Ye C, Wille CK, Nguyen LC, Krautkramer KA, Tomasiewicz JL, Yang SE, Miller BR, LiuWH, Igarashi K, Sridharan R, Tu BP, Cryns VL, Lamming DW, Denu JM (2020) Methyl-metabolite depletion elicits adaptive responses to support heterochromatin stability and epigenetic persistence. Mol. Cell 78(2):210-223. [link]
2013-2019 (Before join the LSI)
Kuang Z, Wang Y, Li Y, Ye C, Ruhn KA, BehrendtCL, Olson EN, Hooper LV (2019) The intestinal microbiota programs diurnal rhythms in host metabolism throughhistone deacetylase 3. Science 365(6460):1428-1434. [link]
Ye C, Sutter BM, Wang Y, Kuang Z, Zhao X, Yu Y, Tu BP (2019) Demethylation of the protein phosphatase PP2A promotes demethylation of histones to enable their function as a methyl group sink.Mol. Cell 73(6):1115-1126. [link]
Ye C and Tu BP (2018) Sink into the Epigenome: Histones as repositories that influence cellular metabolism. Trends Endocrinol Metab. 29(9):626-637. [link]
Ye C, Sutter BM, Wang Y, Kuang Z, Tu BP (2017) A metabolic function for phospholipid and histone methylation.Mol. Cell 66(2):180-193. [link]
Yu W*, Ye C*, and Greenberg ML (2016) Inositol hexakisphosphate kinase 1 (IP6K1) regulates inositol synthesis in mammalian cells. J. Biol.Chem. 291(20):10437-10444.
Ye C, Shen Z, and Greenberg ML (2015) Cardiolipin remodeling: a regulatory hub for modulating cardiolipin metabolism and function. J. Bioenerg. Biomembr. 48(2):113-123.
Shen Z, Ye C, McCain K, and Greenberg ML (2015) The role of cardiolipin in cardiovascular health. BioMed Res. Int. 2015:891707.
Ye C and Greenberg ML (2015) Inositol synthesis regulates activation of GSK-3α in neuronal cells. J. Neurochem.133(2): 73-83.
Ye C*, Lou W*, Li Y, Chatzispyrou IA, Hüttemann M, Lee I, Houtkooper RH, Vaz FM, Chen S, Greenberg ML (2014) Deletion of the cardiolipin-specific phospholipase Cld1 rescues growth and lifespan defects in the tafazzin mutant: Implications for Barth syndrome. J. Biol. Chem. 289(6):3114-25.
Ye C, Bandara WMMS, Greenberg ML (2013) Regulation of inositol metabolism is fine-tuned by inositol pyrophosphates in Saccharomyces cerevisiae. J. Biol. Chem. 288(34):24898-90